Performance over artificial loci. Relative performance on the sets of artificial loci created from the training set (yellow line), HGMD test set (the blue line) and oligogenic test set (the green line). The gray line represents the value expected if there had been no enrichment. The x axis represents the % of the ranked list in which the target gene was found; the y axis represents how frequent that occurrence was. For example, in the training set (the yellow line) the target gene was in the top 30% of the ranked list around 56% of the time.