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Table 2 Summary of results for the simulated data. Numbers of genes declared significant (i.e., significantly differentially expressed) by different numbers of labs and the fixed and random effects meta-analyses in the simulation example. The False Discovery Rate (FDR) for the meta-analyses and each lab separately was controlled at 0.05. There were 21 Integration-Driven Discoveries (IDD's) and 4 Integration-Driven Revisions (IDR's).

From: Combining Affymetrix microarray results

  Fixed Effects Model Random Effects Model
Num. of Labs Declaring Number of Genes Declared Number of Genes Declared
Significance Not Significant Significant Not Significant Significant
0 1152 51 1182 21
1 33 38 64 7
2 3 8 4 4
3 0 4 0 4
4 0 3 0 3
5 0 7 0 7
6 0 26 0 26
  1188 137 1250 72