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Figure 2 | BMC Bioinformatics

Figure 2

From: Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical role in cell-cycle control

Figure 2

Expanded signatures. (A) 210 probesets down regulated by EWS/FLI, p16, and pRB. Sample EWS-FLI1_d0, sample of EWS/FLI dataset analyzed at day 0; Sample p16_0, sample of p16 dataset analyzed at 0 hours; Sample pRB_0, sample of pRB dataset analyzed at 0 hours. Red means up regulation, relative to control conditions (Sample EWS-FLI1_d0 for EWS/FLI dataset; Sample p16_0 for p16 dataset; Sample pRB_0 for pRB dataset), blue means down regulation. (B) 93 probesets up regulated by pRB and down regulated by EWS/FLI. (C) Average of correlation values (Acv) for initial set of probesets identified mining published lists (initial cluster) and for the expanded cluster. Acv are calculated on probesets down regulated by EWS/FLI, pRB, and p16. Error bars represent the standard deviation of the correlation values. (D) Acv calculated for probesets up regulated by pRB and down regulated by EWS/FLI.

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