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Figure 3 | BMC Bioinformatics

Figure 3

From: Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical role in cell-cycle control

Figure 3

Enrichment in Gene Ontology categories. The x axis of the histogram reports the identifier of the Gene Ontology category, the y axis reports -log10 P, where P represents the significance of the enrichment evaluated by GoTM. (A) Analysis of expanded cluster of genes repressed by pRB, p16, and EWS/FLI using, as reference gene list, NCBI Gene identifiers annotated in the Affymetrix HG_U95Av2 platform. Plotted categories show enrichment greater than 5 fold and occur more than 5 times in the expanded cluster. (B) Analysis of expanded cluster of genes repressed by pRB, p16, and EWS/FLI using as reference gene list the two expanded clusters merged. All the significantly enriched categories are plotted (C) Analysis of expanded cluster of genes induced by pRB, and repressed by EWS/FLI using as reference gene list, NCBI Gene identifiers annotated in Affymetrix HG_U95Av2 platform. Only categories enriched more than 5 fold and occuring more than 5 times are represented. (D) Analysis of expanded cluster of genes induced by pRB, and repressed by EWS/FLI using as reference gene list the merger of the two expanded clusters.

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BMC Bioinformatics

ISSN: 1471-2105

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