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Table 4 Overlap of the inferred and experimental human networks with iHOP

From: HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms

  

H_MINT

H_MINT ctrl

Sanger

Sanger ctrl.

OPHID

OPHID ctrl.

HEN

HEN ctrl.

 

Nr of Edges

7658

7658

26590

26590

12887

12887

23332

23332

iHOP* (sentence)

278,452

522 (6.8)

57 (0.7)

857 (3.2)

233 (0.8)

941 (7.3)

88 (0.7)

5293 (22.6)

615 (2.7)

iHOP (pattern)

47,807

229 (3)

9 (0.1)

254 (1)

53 (0.2)

468 (3.6)

14 (0.1)

2675 (11.5)

176 (0.7)

  1. *The iHOP (sentence) network includes interactions between proteins whose names are found in the same sentence in an abstract. iHOP (pattern) is a subnetwork linking proteins found in a pattern of type gene_name_A/verb/ gene_name_B. The networks that are compared with iHOP are described in the main text. The corresponding 'ctrl' networks are scrambled networks containing the same nodes and the same number of edges. For this comparison we mapped all the proteins to Locus Link ids. In this process proteins (and their interactions) that could not be confidently mapped were eliminated from the networks.