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Table 4 Overlap of the inferred and experimental human networks with iHOP

From: HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms

   H_MINT H_MINT ctrl Sanger Sanger ctrl. OPHID OPHID ctrl. HEN HEN ctrl.
  Nr of Edges 7658 7658 26590 26590 12887 12887 23332 23332
iHOP* (sentence) 278,452 522 (6.8) 57 (0.7) 857 (3.2) 233 (0.8) 941 (7.3) 88 (0.7) 5293 (22.6) 615 (2.7)
iHOP (pattern) 47,807 229 (3) 9 (0.1) 254 (1) 53 (0.2) 468 (3.6) 14 (0.1) 2675 (11.5) 176 (0.7)
  1. *The iHOP (sentence) network includes interactions between proteins whose names are found in the same sentence in an abstract. iHOP (pattern) is a subnetwork linking proteins found in a pattern of type gene_name_A/verb/ gene_name_B. The networks that are compared with iHOP are described in the main text. The corresponding 'ctrl' networks are scrambled networks containing the same nodes and the same number of edges. For this comparison we mapped all the proteins to Locus Link ids. In this process proteins (and their interactions) that could not be confidently mapped were eliminated from the networks.