Figure 8
![Figure 8](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1471-2105-7-100/MediaObjects/12859_2005_Article_839_Fig8_HTML.jpg)
Affine transformation with negative translation. Affine transformation of the red and the green signals with negative translation where (a G , a R ) = (-87, -24), (b G ,b R ) = (1.4,0.8). Left: Log-ratios as a function of log-intensities for certain fold changes. Right: Translated log-ratios versus true log-ratios. The slope of a line fitted in the M versus M plot will be larger than one, which is due to the negative translation. The grid and the fold-change curves in the left graph, and the intensity curves in the right graph have been truncated such that x R ,x G ≥ 1.