Table 4 The top 10 matches to BRCA1_HUMAN from the UniProt mouse proteome obtained by searching the Biological Process category with a D-value cutoff of 0.05 (data source: DAG-Edit version 1.419 Rev 3, and EBI goa_mouse.14)
Protein | Summary of functions or protein name |
|---|---|
BRCA1_MOUSE | Plays a central role in DNA repair by facilitating cellular response to DNA repair |
SMRA3_MOUSE | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 |
BCL10_MOUSE | Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. |
INHA_MOUSE | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. |
DDIT3_MOUSE | Growth arrest and DNA-damage-inducible protein GADD153 |
ATM_MOUSE | Involved in signal transduction, cell cycle control and DNA repair. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK |
ASC_MOUSE | Promotes caspase-mediated apoptosis. |
HMG2_MOUSE | High mobility group protein 2 |
CAF1A_MOUSE | Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. |
MLH1_MOUSE | DNA mismatch repair protein Mlh1 |