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Table 4 The top 10 matches to BRCA1_HUMAN from the UniProt mouse proteome obtained by searching the Biological Process category with a D-value cutoff of 0.05 (data source: DAG-Edit version 1.419 Rev 3, and EBI goa_mouse.14)

From: Gene functional similarity search tool (GFSST)

Protein Summary of functions or protein name
BRCA1_MOUSE Plays a central role in DNA repair by facilitating cellular response to DNA repair
SMRA3_MOUSE SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3
BCL10_MOUSE Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK.
INHA_MOUSE Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.
DDIT3_MOUSE Growth arrest and DNA-damage-inducible protein GADD153
ATM_MOUSE Involved in signal transduction, cell cycle control and DNA repair. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK
ASC_MOUSE Promotes caspase-mediated apoptosis.
HMG2_MOUSE High mobility group protein 2
CAF1A_MOUSE Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair.
MLH1_MOUSE DNA mismatch repair protein Mlh1