Example output of GOPET: the first column shows the GO ID, followed by its aspect (molecular function), the confidence value of the prediction and the short description of the GO-term. The example here shows the query results for sequence Xfz4 (Xenopus frizzled 4). Note, that Xfz4 is a maternal mRNA whose carboxyl-terminal half contains putative transmembrane segments. Furthermore, it is homologous to the murine gene product Mfz4, a frizzled transmembrane protein . It has been shown elsewhere, that the C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling .