Table 6 Description of peptides for proteochemometric modelling. The general sequence of the peptides used herein was: Ac-Ser-Pos2-Ser-Pos4-Gly-His-Pos7-Arg-Trp-Gly-Lys-Pro-Val-NH2. Amino acids in Pos2, Pos4, Pos7, and the corresponding description, were as shown.
Peptides | Sequence position | Descriptors | ||||
|---|---|---|---|---|---|---|
Pos2 | Pos4 | Pos7 | Y | F | Y*F | |
α-MSH | Tyr | Met | Phe | -1 | -1 | 1 |
NDP-MSH | Tyr | Nle | D-Phe | -1 | 1 | -1 |
125I-NDP-MSH | 125I-Tyr | Nle | D-Phe | 1 | 1 | 1 |