Skip to main content

Table 1 Values of criteria for functional effectiveness calculated using the GEPs derived from the published experimental datasets.

From: Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock

Experimental Dataset
   Basal DB1 10' a DB2 15' b DB3 10' c DB3 15' c DB3 20' c
Gene expression fold-change with respect to pre-stress situation HXT 1 8 6 5.6 8.6 5.8
  GLK 1 4.8 5.2 5.7 10.5 7.2
  PFK 1 1 0.9 0.5 0.8 0.9
  TDH 1 1.8 1.3 1.7 2.2 1.4
  PYK 1 1.1 1.2 1 1 1
  TPS 1 5 4 9.9 15.6 15.7
  G6PDH 1 3.8 1.8 2.4 5 3.9
Fluxesd VATP 60.2 263.8 222.4 175.0 262.6 199.4
  VTRE 0.0012 0.0535 0.0343 0.1202 0.1830 0.1213
  VNADPH 1.8 7.7 3.7 4.9 10.3 7.7
  1. a: BD1 10': data from Eisen's experiments at 10 min. b: BD2 15': data from Causton's experiments at 15'. c: DB3 10', DB3 15' and DB3 20': data from Gasch's experiments at 10', 15' and 20', respectively. d: Rate of synthesis (mMmin-1).