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Table 1 Values of criteria for functional effectiveness calculated using the GEPs derived from the published experimental datasets.

From: Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock

Experimental Dataset

  

Basal

DB1 10' a

DB2 15' b

DB3 10' c

DB3 15' c

DB3 20' c

Gene expression fold-change with respect to pre-stress situation

HXT

1

8

6

5.6

8.6

5.8

 

GLK

1

4.8

5.2

5.7

10.5

7.2

 

PFK

1

1

0.9

0.5

0.8

0.9

 

TDH

1

1.8

1.3

1.7

2.2

1.4

 

PYK

1

1.1

1.2

1

1

1

 

TPS

1

5

4

9.9

15.6

15.7

 

G6PDH

1

3.8

1.8

2.4

5

3.9

Fluxesd

VATP

60.2

263.8

222.4

175.0

262.6

199.4

 

VTRE

0.0012

0.0535

0.0343

0.1202

0.1830

0.1213

 

VNADPH

1.8

7.7

3.7

4.9

10.3

7.7

  1. a: BD1 10': data from Eisen's experiments at 10 min. b: BD2 15': data from Causton's experiments at 15'. c: DB3 10', DB3 15' and DB3 20': data from Gasch's experiments at 10', 15' and 20', respectively. d: Rate of synthesis (mMmin-1).
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BMC Bioinformatics

ISSN: 1471-2105

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