Figure 10
From: Dissecting trait heterogeneity: a comparison of three clustering methods applied to genotypic data
Novel Data Simulation Algorithm. Simulates trait heterogeneity, locus heterogeneity and gene-gene interactions in an epidemiologically-sound manner. The inputs are penetrance function arrays, which are translated into probability arrays for affecteds and unaffecteds, separately. Then affected and unaffected individuals (with multilocus genotypes) are simulated from those respective arrays.