Figure 7

Complexes that are of size ≥ 6 of the set generated using d _in = 0.7, cp _in = 0.50 and non-overlapping mode. (a) ID, size N, density d, p-value (with Bonferroni correction), a corresponding histogram and the names of the constituent proteins of each complex. The histogram of a complex shows the distribution of its member proteins with respect to 15 functional classes: (1) Cell cycle and DNA processing, (2) Protein with binding function or cofactor requirement (structural or catalytic), (3) Protein fate (folding, modification, destination), (4) Biogenesis of cellular components, (5) Cellular transport, transport facilitation and transport routes, (6) Metabolism, (7) Interaction with the cellular environment, (8) Transcription, (9) Energy, (10) Cell rescue, defense and virulence, (11) Cell type differentiation, (12) Cellular communication/signal transduction mechanism, (13) Protein activity regulation, (14) Protein synthesis, and (15) Transposable elements, viral and plasmid proteins. A protein may belong to more than one functional class. The scaling of a histogram is according to the size of the corresponding complex. The highest column/columns of a histogram are colored as red. (b) The network of the complex 19 of Fig 7(a).