Skip to main content

Table 5 Associations of NBS1 with breast cancer status and age-at-diagnosis using a composite genotype analysis in the Case-Control cohort1.

From: PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size

 

Breast Cancer Status

Age-at-Diagnosis

Model

Odds ratio (Empirical 95% CI)

p

Means test

p

Dom-Dom

1.23 (0.85, 1.79)

0.28

0.30

0.77

Rec-Rec

0.49 (0.18, 1.29)

0.13

0.005

0.99

Rec-Dom

0.56 (0.25, 1.27)

0.16

-0.59

0.55

Dom-Rec

0.90 (0.48, 1.71)

0.77

-0.79

0.43

  1. 1Results for this table are derived from requiring specific inheritance models for the two tSNPs for NBS1 (rs12680687 and rs709816). Dom = dominant, Rec = recessive.