Figure 1
From: A hidden Markov model approach for determining expression from genomic tiling micro arrays
These plots summarise the Naef & Magnasco (2003) inspired normalisation procedure tested in the development of ExpressHMM. Sub-figure A displays fitted fluorescence contributions of the nucleotides A, C, G and T at each sequence position in the probe. Sub-figure B displays the effects of normalising chips using PM .estimate's on the data distribution.