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Table 4 The tRNA dataset. Base pairs from the top-ranked (NTFirst) motif were used as structural constraints for MFOLD. The table presents the PPV and sensitivity for the application of MFOLD alone as well as the combined approach onto the tRNA dataset. The number in between parentheses represents the number of sub-optimal structures reported with similar performance measures.

From: Identification of consensus RNA secondary structures using suffix arrays

Id

Method

% PPV

% Sensitivity

RD0260

MFOLD (2)

28.6–29.2

28.6–33.3

 

MFOLD (1)

66.7

57.1

 

MFOLD (1)

57.1

57.1

 

Seed NTFirst + MFOLD

100.0

100.0

RD1140

MFOLD (1)

100.0

100.0

 

Seed NTFirst + MFOLD

100.0

100.0

RD2640

MFOLD (1)

63.6

66.7

 

MFOLD (2)

18.2

19.0

 

Seed NTFirst + MFOLD

100.0

100.0

RE2140

MFOLD (1)

87.0

95.2

 

MFOLD (1)

69.6

76.2

 

Seed NTFirst + MFOLD

91.3

100.0

RE6781

MFOLD (4)

28.0–31.8

33.3

 

Seed NTFirst + MFOLD

100.0

100.0