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Figure 8 | BMC Bioinformatics

Figure 8

From: Optimizing amino acid substitution matrices with a local alignment kernel

Figure 8

Distribution of Z score of the LA kernel. The curve shows that the Z scores of the LA kernel of non-homologous sequences of the same length randomly shuffled 100000 times follow the Extreme Value Distribution ( e ( ( a − x ) / b − e ( ( a − x ) / b ) ) / b MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqGGOaakcqWGLbqzdaahaaWcbeqaaiabcIcaOiabcIcaOiabdggaHjabgkHiTiabdIha4jabcMcaPiabc+caViabdkgaIjabgkHiTiabdwgaLnaaCaaameqabaGaeiikaGIaeiikaGIaemyyaeMaeyOeI0IaemiEaGNaeiykaKIaei4la8IaemOyaiMaeiykaKcaaSGaeiykaKcaaOGaei4la8IaemOyaigaaa@464A@ with a = -5.1, b = 6.7).

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