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Table 2 The self-consistency and jackknife results for the sequence-based method trained by the six combinations listed in table 1.

From: Demonstration of two novel methods for predicting functional siRNA efficiency

 

Dieter's Dataset

Satron's Dataset

 

Self-Consistency

Jackknife

Self-consistency

Jackknife

Cut-Off 0.7

    

Accuracy

89.88%

89.35%

76.83%

70.94%

Sensitivity

94.28%

93.87%

75.18%

68.09%

Specificity

87.98%

87.39%

77.38%

71.90%

Pearson

0.658

0.6594

0.4816

0.4021

ROC

0.975

0.9698

0.8333

0.7557

Cut-Off 0.6

    

Accuracy

90.79%

89.47%

75.04%

70.59%

Sensitivity

91.27%

89.49%

74.72%

67.42%

Specificity

90.33%

89.45%

75.20%

72.06%

Pearson

0.8298

0.8264

0.4699

0.3944

ROC

0.9735

0.9686

0.8169

0.7381

Cut-Off 0.5

    

Accuracy

90.25%

89.43%

77.18%

70.23%

Sensitivity

88.33%

87.70%

75.57%

68.78%

Specificity

93.85%

92.67%

78.24%

71.18%

Pearson

0.8288

0.8278

0.4446

0.3851

ROC

0.9751

0.97

0.8353

0.7675