Figure 1
From: Accelerating the reconstruction of genome-scale metabolic networks
Schematic representation of the AUTOGRAPH-method. The method consists of two parts, A and B. Part A includes the orthology prediction between genes of the query genome and the reference genomes from which there is a manually curated metabolic network available. In part B the gene-reaction associations are extracted from the manually curated networks. Subsequently, orthology will be combined with the gene-reaction association data. This allows reaction transfer to genes of the query genome.