Table 1 Five of the most overrepresented GO biological processes and molecular functions that corresponding to Yersinia pestis infection.
From: Array2BIO: from microarray expression data to functional annotation of co-regulated genes
Biological processes | Enrichment | p-value | Observed/expected | Total category count |
|---|---|---|---|---|
response to biotic stimulus | 4.16 | 1.85e-14 | 37/8.9 | 873 |
response to stress | 4.05 | 6.37e-13 | 34/8.4 | 824 |
immune response | 4.36 | 3.33e-12 | 30/6.9 | 676 |
response to pest, pathogen or parasite | 5.30 | 4.48e-12 | 25/4.7 | 463 |
defense response | 3.99 | 1.27e-11 | 31/7.8 | 762 |
Molecular functions | Enrichment | p-value | Observed/expected | Total category count |
chemokine activity | 17.07 | 1.72e-8 | 8/0.5 | 46 |
chemokine receptor binding | 17.07 | 1.72e-8 | 8/0.5 | 46 |
G-protein-coupled receptor binding | 15.40 | 4.01e-8 | 8/0.5 | 51 |
cytokine activity | 5.27 | 7.35e-6 | 11/2.1 | 205 |
transcription factor activity | 2.48 | 2.92e-4 | 18/7.3 | 712 |