Table 7 Evaluation of the database content for the top 50 genes in multiple sclerosis.
From: The Autoimmune Disease Database: a dynamically compiled literature-derived database
AIDB and GAD | Genes and PubMed references only in AIDB | |||||
|---|---|---|---|---|---|---|
Ranking Method | # MS associated Genes | # correctly retrieved PubMed references | # MS associated Genes | # correctly retrieved PubMed references | Examples True Recognition | Examples False Recognition |
RANK based Top 50 | 3/50 | 67% (2/3) | 47/50 | 81% (38/47) | MMP27, IFNA16, ADAMTS14 | IBD2, Bw3, ABHs, THADA |
Frequency based Top 50 | 24/50 | 79% (19/24) | 26/50 | 85% (22/26) | CCL5, MMP9, GFAP, CCL2, VCAM1, NOS2A | CD4, CD8A, CD86, CD25, CD28, CDR3 |