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Table 7 Evaluation of the database content for the top 50 genes in multiple sclerosis.

From: The Autoimmune Disease Database: a dynamically compiled literature-derived database

  AIDB and GAD Genes and PubMed references only in AIDB
Ranking Method # MS associated Genes # correctly retrieved PubMed references # MS associated Genes # correctly retrieved PubMed references Examples True Recognition Examples False Recognition
RANK based Top 50 3/50 67% (2/3) 47/50 81% (38/47) MMP27, IFNA16, ADAMTS14 IBD2, Bw3, ABHs, THADA
Frequency based Top 50 24/50 79% (19/24) 26/50 85% (22/26) CCL5, MMP9, GFAP, CCL2, VCAM1, NOS2A CD4, CD8A, CD86, CD25, CD28, CDR3
  1. Evaluation of the quality of the 50 highest ranked genes in multiple sclerosis for the RANK (first row) and the frequency (second row) based methods. The number of genes that are also in GAD (1st column) and the number of correctly retrieved PubMed references (2nd column) are listed in the left part of the table. The right part (column 3–6) contains the results for the genes that were exclusively found in AIDB. Examples for true recognition are given in column 5 and examples for false recognition are given in column 6.