Figure 6

Prediction paths for KcsA. Each of the three different growing paths ((a), (b) and (c)) is characterized by selection, at each growing step, of the best scored solution within the most populated cluster/s, characterized also by similar and significantly low MemTop index. The number of solutions filtered at each step is reported under the arrow. The circle on the arrow indicates the probe, whereas the circles that precede the arrow are the targets. The monomers that constitute these targets are indicated by gray circles except for the last added monomer/s, which are indicated by white circle/s and by the solution number in the ZDOCK output list. The final oligomer is indicated by a string of letters and characters in a way that each subunit is associated with the docking solution. In detail, the upper case letter indicates the subunit, whereas the letter "s" followed by a number indicates the solution number in the ZDOCK output list. Finally, the C_α-RMSD (Å) between native and predicted quaternary structures is also reported. All the amino acid residues have been included in C_α-RMSD calculations.