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Figure 2 | BMC Bioinformatics

Figure 2

From: PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs

Figure 2

Potential interaction sites between YNL243W and YBL007C. PIPE can successfully determine the previously known sites of interaction between the two proteins YNL243W and YBL007C. It was previously shown that the region 310–768 in protein YNL243W is responsible for its interaction with amino acids 118–361 in protein YBL007C. Visualized by its highest pick with a score of 45, PIPE has successfully detected an interaction between YNL243W and YBL007C via their corresponding amino acid regions 350–410 and 100–250, respectively. A second highest pick with a score of 42 also suggest a second site of interaction between the two proteins. According to PIPE analysis it is possible that the C-terminal end of the YBL007C protein may also serve as a site of interaction.

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BMC Bioinformatics

ISSN: 1471-2105

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