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Table 4 MAD for the GeneLogic Dilution Study. Pooled MAD of the computed relative mRNA proportions in mixing experiments 25, 50, and 75 for different chip evaluation methods. The respective MAD is calculated with regard to the target values p S = 0.25, 0.50, and 0.75. Notation according to Table 3.

From: Robust computational reconstitution – a new method for the comparative analysis of gene expression in tissues and isolated cell fractions

evaluation method

mix 25

mix 50

mix 75

  

lr

 

lr

 

lr

MAS-S t

7.7

6.9

7.3

8.4

0.2

3.4

MAS-S t clr

7.4

3.8

6.1

6.1

1.2

1.4

MAS-S t q

8.4

5.9

9.0

7.7

1.5

2.2

MAS-S t c

9.6

7.5

9.2

8.8

2.0

3.6

MAS-S mean

8.2

6.0

7.9

7.7

1.2

2.6

MAS-C t

6.0

5.7

6.2

7.2

2.0

2.2

MAS-C t clr

7.1

3.9

7.0

5.9

1.1

1.0

MAS-C t q

7.8

3.7

7.8

6.5

1.7

2.6

MAS-C t c

6.2

5.9

8.2

7.3

3.5

2.7

MAS-C mean

6.8

4.8

7.3

6.7

2.1

2.1

RMA

9.9

8.9

8.4

7.8

0.8

1.1

MBEI

8.0

8.2

8.1

7.5

1.7

1.0