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Table 3 Significant TFBS of QTC subclusters from the serum response data set.

From: Analysis of promoter regions of co-expressed genes identified by microarray analysis

Cluster Time point Number of genes Significant TFBS present in all promoters of a given cluster1 DBTF part of gene cluster2
11A 3 8 AP1, ETS1, RFX1 (SRF 3/8)  
11B 3 12 Significant TFBS but not present in all  
1A 4 14 No significant TFBS  
1B 4 8 CEBPDELTA  
1C 4 21 Significant TFBS but not present in all  
1D 4 17 No significant TFBS  
6A 4 20 AP1, FOXO4, GATA1, HFH3, HNF3ALPHA, HNF3B (MYCMAX 12/20))  
6B 4 7 ARNT, HIF1, MYCMAX, NMYC, USF  
6C 4 24 No significant TFBS MYC, SRF
8A 4 17 Significant TFBS but not present in all  
8B 4 10 Significant TFBS but not present in all  
4A 5 11 No significant TFBS  
4B 5 10 CETS1P54, ETS1, ETS2, IK1  
9A 5 6 AP1, BARBIE (SRF 2/6)  
9B 5 15 No significant TFBS  
9C 5 13 Significant TFBS but not present in all (SRF 3/13)  
14A 5 5 No significant TFBS  
14B 5 6 Significant TFBS but not present in all  
14C 5 10 Significant TFBS but not present in all  
12A 5 11 Significant TFBS but not present in all  
12B 5 15 RFX1  
7A 6 10 AP1, BARBIE, CETS1P54, CREL, FOXJ2, FOXO4, GATA1, HAND1E47, HFH3, HNF3ALPHA, HNF3B, IK1, NKX25, RFX1 (MYCMAX 5/10, TCF4 6/10) TCF4
7B 6 8 No significant TFBS  
7C 6 14 FOXO4  
7D 6 11 Significant TFBS but not present in all  
15A 6 17 Significant TFBS but not present in all  
15B 6 6 No significant TFBS  
5A 7 13 AREB6, IK1  
5B 7 5 CAAT, NFY  
2A 9 19 No significant TFBS  
2B 9 16 Significant TFBS but not present in all  
2C 9 16 AP1 (SRF 4/16)  
2D 9 7 ARNT, HIF1, MYCMAX, NMYC, USF  
10A 9 7 AP1, BARBIE, CAAT, CDPCR3HD, CABPDELTA, E2F1, ETS1, FOXJ2, FOXO4, GATA, GATA1, GFI1, HFH3, HFH8, HNF3ALPHA, IPF1, LMO2COM, MTATA, MYOD, TGIF (MYCMAX 4/7, TCF4 5/7)  
10B 9 16 No significant TFBS  
13A 10 10 GATA1  
13B 10 12 No significant TFBS  
3A 12 8 E2F, E2F1 (E2F1DPIRB (7/8), E2F1DP2 (5/8) E2F4DP2 (5/8) E2F
3B 12 12 GATA1  
16A -3 7 No significant TFBS  
16B - 18 No significant TFBS  
17A - 8 Significant TFBS but not present in all  
17B - 11 No significant TFBS  
  1. 1 TFBS in parenthesis are present in the fraction of promoters indicated.
  2. 2 DNA binding transcription factors present in the respective subclusters.
  3. 3 Indicates flat profiles.