Table 3 Significant TFBS of QTC subclusters from the serum response data set.
From: Analysis of promoter regions of co-expressed genes identified by microarray analysis
Cluster | Time point | Number of genes | Significant TFBS present in all promoters of a given cluster1 | DBTF part of gene cluster2 |
|---|---|---|---|---|
11A | 3 | 8 | AP1, ETS1, RFX1 (SRF 3/8) | |
11B | 3 | 12 | Significant TFBS but not present in all | |
1A | 4 | 14 | No significant TFBS | |
1B | 4 | 8 | CEBPDELTA | |
1C | 4 | 21 | Significant TFBS but not present in all | |
1D | 4 | 17 | No significant TFBS | |
6A | 4 | 20 | AP1, FOXO4, GATA1, HFH3, HNF3ALPHA, HNF3B (MYCMAX 12/20)) | |
6B | 4 | 7 | ARNT, HIF1, MYCMAX, NMYC, USF | |
6C | 4 | 24 | No significant TFBS | MYC, SRF |
8A | 4 | 17 | Significant TFBS but not present in all | |
8B | 4 | 10 | Significant TFBS but not present in all | |
4A | 5 | 11 | No significant TFBS | |
4B | 5 | 10 | CETS1P54, ETS1, ETS2, IK1 | |
9A | 5 | 6 | AP1, BARBIE (SRF 2/6) | |
9B | 5 | 15 | No significant TFBS | |
9C | 5 | 13 | Significant TFBS but not present in all (SRF 3/13) | |
14A | 5 | 5 | No significant TFBS | |
14B | 5 | 6 | Significant TFBS but not present in all | |
14C | 5 | 10 | Significant TFBS but not present in all | |
12A | 5 | 11 | Significant TFBS but not present in all | |
12B | 5 | 15 | RFX1 | |
7A | 6 | 10 | AP1, BARBIE, CETS1P54, CREL, FOXJ2, FOXO4, GATA1, HAND1E47, HFH3, HNF3ALPHA, HNF3B, IK1, NKX25, RFX1 (MYCMAX 5/10, TCF4 6/10) | TCF4 |
7B | 6 | 8 | No significant TFBS | |
7C | 6 | 14 | FOXO4 | |
7D | 6 | 11 | Significant TFBS but not present in all | |
15A | 6 | 17 | Significant TFBS but not present in all | |
15B | 6 | 6 | No significant TFBS | |
5A | 7 | 13 | AREB6, IK1 | |
5B | 7 | 5 | CAAT, NFY | |
2A | 9 | 19 | No significant TFBS | |
2B | 9 | 16 | Significant TFBS but not present in all | |
2C | 9 | 16 | AP1 (SRF 4/16) | |
2D | 9 | 7 | ARNT, HIF1, MYCMAX, NMYC, USF | |
10A | 9 | 7 | AP1, BARBIE, CAAT, CDPCR3HD, CABPDELTA, E2F1, ETS1, FOXJ2, FOXO4, GATA, GATA1, GFI1, HFH3, HFH8, HNF3ALPHA, IPF1, LMO2COM, MTATA, MYOD, TGIF (MYCMAX 4/7, TCF4 5/7) | |
10B | 9 | 16 | No significant TFBS | |
13A | 10 | 10 | GATA1 | |
13B | 10 | 12 | No significant TFBS | |
3A | 12 | 8 | E2F, E2F1 (E2F1DPIRB (7/8), E2F1DP2 (5/8) E2F4DP2 (5/8) | E2F |
3B | 12 | 12 | GATA1 | |
16A | -3 | 7 | No significant TFBS | |
16B | - | 18 | No significant TFBS | |
17A | - | 8 | Significant TFBS but not present in all | |
17B | - | 11 | No significant TFBS |