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Figure 12 | BMC Bioinformatics

Figure 12

From: Fast index based algorithms and software for matching position specific scoring matrices

Figure 12

Restricted probability computation. Computation of the partial cumulative distribution function. Observe that in order to determine T m i n P MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBamrtHrhAL1wy0L2yHvtyaeHbnfgDOvwBHrxAJfwnaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaWaaeGaeaaakeaacqWGubavieGacqWFTbqBcqWFPbqAcqWFUbGBdaWgaaWcbaGaemiuaafabeaaaaa@3D07@ (π, M) for π = 0.3 we do not have to calculate the complete distribution in the score range [scmin(M), scmax(M)]. It is sufficient to calculate only the upper end (green area) starting with scmax(M) until ℙ[X ≥ S] ≥ π.

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