Table 2 Results for skeletal-muscle-specific human genes. Most significant TFBSs detected in the muscle data set by TFM-Explorer, TOUCAN, OTFBS, and oPOSSUM using sequences that were 2 kb upstream. The TRANSFAC vertebrate matrix collection was used with TOUCAN and OTFBS, and JASPAR vertebrate matrices were used with TFM-Explorer and oPOSSUM. TFs with experimentally verified sites in the data set are marked with *.

Rank

PWM

Window

P-value

1

*

SRF

[-0224: -0091]

7.869e-06

2

*

MEF2

[-0060: -0030]

2.350e-05

3

*

MZF_1-4

[-1431: -0576]

1.678e-04

4

Staf

[-1950: -1311]

2.539e-04

5

Irf-2

[-1892: -1592]

3.002e-04

6

NRF-2

[-0779: -0324]

3.180e-04

7

Brachyury

[-0307: -0048]

4.503e-04

8

Bsap

[-1911: -0978]

4.800e-04

9

cEBP

[-1733: -1679]

6.032e-04

10

*

MZF_5-13

[-1633: -1078]

7.141e-04

Rank

PWM

P-value

1

HEN1_01

8.567e-02

2

*

MEF2_02

1.021e-01

3

RSRFC4_01

1.129e-01

4

TAL1BETAITF2_01

1.311e-01

5

STAT5A_01

1.856e-01

6

TAL1BETAE47_01

2.322e-01

7

YY1_01

2.391e-01

8

STAT5B_01

2.534e-01

9

*

MEF2_03

3.056e-01

10

CDC5_01

3.134e-01

Rank

PWM

P-value

1

YY1_02

2.047e-06

2

*

MZF1_02

2.763e-06

3

*

MEF2_02

9.493e-06

Rank

PWM

P-value

1

*

MEF2

1.768e-04

2

Hen-1

3.730e-04

3

SRY

1.531e-03

4

c-MYB_l

1.780e-03

5

S8

2.983e-03

6

HFH-3

2.994e-03

7

*

SP1

3.220e-03

8

*

MZF_5-13

3.675e-03

9

Nkx

6.399e-03

10

RORalfa-2

7.747e-03