A simple method to combine multiple molecular biomarkers for dichotomous diagnostic classification

BMC Bioinformatics

Table 1 The publicly available datasets used in the current study

Characteristic	Dataset #1		Dataset #2		Dataset #3		Dataset #4
Authors	Petricoin et al, 2002 [19]		Gordon et al, 2002 [18]		Golub et al, 1999 [17]		van't Veer et al 2002 [20]
Dataset alias	OvCa		LuMe		LLML		BrCa
Biomarker	Proteomic mass spectra		Gene expression		Gene expression		Gene expression
# Biomarkers	15,154		12,533		7,129		24,481
Diagnostic classes	Ovarian cancer	Normal	Lung adeno-carcinoma	Mesothelioma	Acute lymphocytic leukemia	Acute myeloid leukemia	Metastasis within 5 years	Metastasis after 5 years
N (Total)	162	91	150	31	46	26	34	44
N (Training)	83	49	16	16	27	11	17	26
N (Test set)	79	42	134	15	19	15	17	18

ISSN: 1471-2105