From: Protein kinases associated with the yeast phosphoproteome
Substrate protein | Function * | Predicted protein kinase | Function * | Phosphopeptide ** | Scansite score *** | Estimated probability **** |
---|---|---|---|---|---|---|
Cdc47p | DNA replication | CK2 group ***** | G1/S and G2/M transition of mitotic cell cycle, cell ion homeostasis, cell polarity, flocculation, regulation of transcription (Pol I and Pol III promoters), response to DNA damage, regulation of DNA replication | TMDT DQE | 0.212 | 0.25 |
Ede1p | Endocytosis | CK1 group ****** | Cellular morphogenesis, cytokinesis, endocytosis, DNA repair, cell growth, chromosome segregation, meiosis, mitosis, nuclear division | DGES VS SIQ | 0.062 | 0.9 |
Ysc84p | Actin organization, endocytosis | CK1 group | Cellular morphogenesis, cytokinesis, endocytosis, DNA repair, cell growth, chromosome segregation, meiosis, mitosis, nuclear division | DFDS EDE | 0.062 | 0.9 |
Pan1p | Endocytosis, cytokinesis, budding | CK1 group | Cellular morphogenesis, cytokinesis, endocytosis, DNA repair, cell growth, chromosome segregation, meiosis, mitosis, nuclear division | ASAS STS | 0.1 | 0.8 |
Sec4p | Rab GTPase (cytokinesis, exocytosis, polar budding) | CK1 group | Cellular morphogenesis, cytokinesis, endocytosis, DNA repair, cell growth, chromosome segregation, meiosis, mitosis, nuclear division | RTVS ASS GNG | 0.082 | 0.85 |
Sec3p | Cytokinesis, cell polarity | Cdc15p | Cytokinesis, regulation of exit from mitosis | RTIS GSS AHH | 0.232 | 0.15 |
Hsp26p | Chaperone, stress response | Mds1p | Proteolysis, response to stress, sporulation | EVSS QES WGN | - ******* | Â |
Nth1p | Trehalose hydrolysis, stress response | Yfl033cp | Regulation of meiosis, stress response | RRGS EDD | 0.082 | 0.85 |
Hxt2p | Hexose transport | Sha3p | Glucose transport, transcriptional regulation (Pol II promoter) | QQTS IHS TPI | 0.275 | 0.05 |
Shp1p | Glycogen metabolism, sporulation | Snf1p | AMP-activated protein kinase, cell adhesion, response to nitrogen starvation, filamentous growth, glucose metabolism, regulation of carbohydrate metabolism | RKGS TS PEP | 0.145 | 0.6 |
Tps3p | Trehalose phosphatase (carbohydrate metabolism, stress response) | Snf1p | AMP-activated protein kinase, cell adhesion, response to nitrogen starvation, filamentous growth, glucose metabolism, regulation of carbohydrate metabolism | RTSS SMS VGN | 0.102 | 0.8 |
Mcm3p | DNA helicase, initiation of DNA replication | Sgv1p | Transcription | NSGS PIK | 0.082 | 0.85 |
Swi4p | Transcription factor (cell cycle) | CK2 group | G1/S and G2/M transition of mitotic cell cycle, cell ion homeostasis, cell polarity, flocculation, regulation of transcription (Pol I and Pol III promoters), response to DNA damage, regulation of DNA replication | KSTS ETS | 0.168 | 0.5 |
Rpa190p | RNA polymerase subunit (transcription) | CK2 group | G1/S and G2/M transition of mitotic cell cycle, cell ion homeostasis, cell polarity, flocculation, regulation of transcription (Pol I and Pol III promoters), response to DNA damage, regulation of DNA replication | DKES DS DS EDE | 0.104, 0.06, 0.02 | 0.8, 0.9, 0.99 |
Mob1p | Protein kinase regulation (cell cycle regulation) | Ume5p | Cyclin-dependent protein kinase, meiosis, regulation of transcription (Pol II promoter) | VLTT PKR | 0 | 0.99 |
Abp1p | Actin binding (cell polarity) | Cdc28p | Cyclin-dependent protein kinase, regulation of mitosis and meiosis | PSKS PAP | 0.145 | 0.6 |
Abp1p | Actin binding (cell polarity) | Cdc28p | Cyclin-dependent protein kinase, regulation of mitosis and meiosis | PVKT PS PAP | 0.125 | 0.75 |
Crn1p | Actin filament organization | Cdc28p | Cyclin-dependent protein kinase, regulation of mitosis and meiosis | APKS PS PLK | 0.145 | 0.6 |
Pea2p | Actin filament organization, cell polarity, polar budding | Hog1p | Actin filament organization, osmoregulation, transcriptional regulation (Pol II promoter) | NTSS PPI | 0.102 | 0.8 |
Spc98p | Cytoskeleton component (microtubule nucleation, mitotic spindle assembly) | Ssk2p | MAPKKK, actin cytoskeleton organization and biogenesis, osmosensory signaling pathway | ERRS MVS SPN | 0.121 | 0.75 |
Npr1p | Protein kinase (regulation of nitrogen utilization) | Snf1p | AMP-activated protein kinase, cell adhesion, response to nitrogen starvation, filamentous growth, glucose metabolism, regulation of carbohydrate metabolism | RQSS IYS | 0.149 | 0.6 |
Shp1p | Glycogen metabolism, sporulation | Mds1p | Proteolysis, response to stress, sporulation | RKGS TS PEP | 0.082 | 0.85 |
Ydl223cp | Cellular morphogenesis | CK1 group | Cellular morphogenesis, cytokinesis, endocytosis, DNA repair, cell growth, chromosome segregation, meiosis, mitosis, nuclear division | STHS AEH | 0.1 | 0.8 |
Ydl223cp | Cellular morphogenesis | Hsl1p | Cell cycle regulation (G2/M transition of mitotic cell cycle), cell morphogenesis checkpoint, septin checkpoint) | AEHT PRH | 0.127 | 0.75 |
Fpr4p | Peptidyl-prolyl cis-trans isomerase | CK1 group | Cellular morphogenesis, cytokinesis, endocytosis, DNA repair, cell growth, chromosome segregation, meiosis, mitosis, nuclear division | EDES ES EQE | 0, 0.082 | 0.99, 0.85 |
Fpr4p | Peptidyl -prolyl cis-trans isomerase | CK2 group | G1/S and G2/M transition of mitotic cell cycle, cell ion homeostasis, cell polarity, flocculation, regulation of transcription (Pol I and Pol III promoters), response to DNA damage, regulation of DNA replication | EDES ES EQE | 0.084, 0.149 | 0.85, 0.6 |