Figure 11
From: The accuracy of several multiple sequence alignment programs for proteins
Number of gaps inserted by programs relatively to the known alignment. The curves show the difference in the number of gaps relative to the known alignment generated by Simprot. Kalign had the smallest difference for most of the sequence lengths, while POA was the program with the largest difference. Above zero are programs that do not generate a guide tree for multiple alignment, while below zero are the programs that do generate a guide tree.