Using local gene expression similarities to discover regulatory binding site modules

BMC Bioinformatics

Table 3 PCC evaluation

Previous studies	PCC
Segal et al. [26] Cell Cycle, 17 modules	0.365
Segal et al. [25] 48 modules	0.152
Beer et al. [24] 49 modules	0.182
Hvidsten et al. [4] Cell cycle	0.353
Present method	PCC
corr. 0.6, 1316 rules	0.359 (0.383)
corr. 0.7, 807 rules	0.458 (0.452)
corr. 0.75, 643 rules	0.496 (0.479)
corr. 0.8, 487 rules	0.545 (0.505)

Comparison of pairwise co-regulation coefficient for rules obtained in this study with gene groups from other studies (values for generalized rules are shown in brackets). Correlation thresholds used in our clustering procedure are shown in the left column.

ISSN: 1471-2105