CoXpress: differential co-expression in gene expression data

BMC Bioinformatics

Table 1 Differentially co-expressed groups from the Golub dataset

group	N	t1	t2	pr.g2	mean.corr1	mean.corr2	robustness
3	34	155.6977	0.175907	0.4439	0.70126	0.002587	901
62	7	59.75635	-1.06598	0.876	0.7201	-0.09352	1000
121	11	54.77229	1.835753	0.065	0.679399	0.085609	926
21	12	51.18428	-0.83765	0.8032	0.659053	-0.03528	1000
79	7	50.37868	0.830252	0.2021	0.724548	0.063511	914
78	10	50.376	1.040897	0.1614	0.655953	0.049546	950
131	8	42.89021	1.744949	0.0787	0.668891	0.144298	760
157	7	41.89854	-0.1536	0.5177	0.696409	-0.01012	1000
472	7	36.4184	-0.56951	0.6958	0.642614	-0.04193	1000
193	7	32.0097	-0.06639	0.4814	0.707166	-0.00404	974

Differentially co-expressed groups from the ALL/AML dataset of Golub et al [21]. Group is the group number, N is the group size, t1 and t2 are the observed t-statistics in the ALL and AML subsets, pr.g1 and pr.g2 are the probability of randomness statistics for the ALL and AML subsets, mean.corr1 and mean.corr2 are the mean pairwise correlation coefficients for the genes in the ALL and AML cases and robustness is the number of times that the group was differentially co-expressed in 1000 randomly resampled data sets using only 75% of the observations in each leukaemia subtype. Groups are ordered by t1. The table has been filtered such that pr.g1 ≤ 0.05, pr.g2 ≥ 0.05 and N ≥ 7.

ISSN: 1471-2105