Figure 1

Clustering coefficients in large-scale Y2H interaction networks. Clustering coefficients (A) and the ratio to clustering coefficients of random graphs [31] having the same size (B) are shown for the following interaction networks: yeast interactions from DIP [33] and the Y2H studies by Ito et al. [2] and Uetz et al. [1]; C. elegans interactions by Li et al. [3]; drosophila interactions by Giot et al. [4]; P. falciparum interactions by LaCount et al. [5]; and human interactions from the studies of Rual et al. [6] and Stelzl et al. [7]. Only high confidence interactions were considered for the Ito, Li and Giot data set and self-edges were ignored for the calculation of clustering coefficients.