Table 1 GO terms revealed by comparing mouse oocyte and preimplantation embryonic transcriptomes F: molecular function. P: biological process. C: cellular component
From: GO-Diff: Mining functional differentiation between EST-based transcriptomes
GO category | GO name space | EST Coverage Ratio (embryos/oocyte) | Corrected P_value |
|---|---|---|---|
Protein biosynthesis | P | 3.0 | 1.3E-17 |
Ribosome | C | 4.9 | 9.4E-15 |
Ribonucleoprotein complex | C | 3.2 | 3.6E-14 |
Signal transduction | P | 0.61 | 5.0E-07 |
Cytosolic ribosome (sensu Eukarya) | C | 5.3 | 7.3E-06 |
M phase of meiotic cell cycle | P | 0.32 | 4.8E-05 |
Translational elongation | P | 7.0 | 1.0E-04 |
DNA replication and chromosome cycle | P | 0.072 | 2.1E-04 |
DNA topoisomerase type I activity | F | 0 | 3.8E-04 |
Ubiquitin cycle | P | 0.63 | 5.6E-04 |
Ubiquitin conjugating enzyme activity | F | 0.38 | 8.3E-04 |
Fertilization (sensu Metazoa) | P | 21 | 1.9E-03 |
Homologous chromosome segregation | P | 0.14 | 3.4E-03 |
Ubiquitin-protein ligase activity | F | 0.53 | 3.4E-03 |
Ribosome biogenesis and assembly | P | 2.5 | 4.2E-03 |
DNA topological change | P | 0.057 | 5.2E-03 |
Lyase activity | F | 18 | 6.3E-03 |
Response to DNA damage stimulus | P | 0.50 | 1.8E-02 |
Chromatin remodeling | P | 0.35 | 2.0E-02 |
Amine biosynthesis | P | 15 | 2.7E-02 |
Transcriptional repressor complex | C | 0.10 | 4.5E-02 |
Chromatin remodeling complex | C | 0.25 | 4.6E-02 |
Induction of apoptosis via death domain Receptors | P | 0.32 | 5.6E-02 |
Translation elongation factor activity | F | 2.8 | 5.9E-02 |
Apical junction complex | C | 0.27 | 6.3E-02 |
Lysosome | C | 3.6 | 6.5E-02 |
DNA repair | P | 0.52 | 6.8E-02 |
Sodium ion homeostasis | P | 0.079 | 6.8E-02 |
Lung development | P | 0.13 | 7.6E-02 |
Chaperone cofactor dependent protein folding | P | 12 | 8.5E-02 |