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Table 4 F-to-E/Q/K replacements versus all 190 possible replacement patterns

From: Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding proteins

  all pairs F-to-E/Q/K F-to-E F-to-K F-to-Q
replacements* 5,918,700 15,454 5,922 5,815 3,717
average probability** 0.641 0.567 0.563 0.564 0.577
distinct families 1,820 1,457 1,142 1,160 1,068
average members/family 46.9 54.1 60 60.8 62.5
distinct alignment sites 491,794 13,169 5,347 5,181 3,424
average substitution rate/site 1.12 1.48 1.44 1.49 1.52
sites with PDB data 442,102 12,101 4,932 4,734 3,172
protein surface sites 54% 72% 73% 74% 65%
distinct branches 148,522 11,800 5,235 5,089 3,456
average branch length 0.207 0.697 0.807 0.782 0.761
  1. *Detected as sites where the most probable parent and child residues were different.
  2. **The average product of probabilities for the parent and child residues.