Table 2 Numbers of genes whose functions are related to carcinogenesis and whose expression was altered by aristolochic acid in kidney and liver of rats.
Functions | Kidney | Liver |
|---|---|---|
Drug Metabolism | 14 | 10 |
DNA replication, recombination and repair | 2 | 4 |
Genetic disorder | 17 | 6 |
Cell cycle | 26 | 13 |
Cellular development | 18 | 7 |
Cellular function and maintenance | 16 | 5 |
Cell-to-cell and signaling and interaction | 41 | 8 |
Cell morphology | 36 | 15 |
Cell death | 54 | 2 |
Cellular growth and proliferation | 37 | 8 |
Tumor morphology | 19 | 8 |
Cancer | 92 | 25 |
Total | 372 | 111 |