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Table 2 8-SPT as an example of how variation in chemical nomenclature affects information retrieval. Here, Ovid was used to map 5 variations of the chemical name 8-SPT to subject headings. Only adenosine and theophylline were common to each variant tested. 8-SPT is an adenosine receptor antagonist. For comparison, PubMed retrieved 341 unique records when using each of the keywords separated by "OR" in the query.

From: A scalable machine-learning approach to recognize chemical names within large text databases

Chemical Name mapped to term(s) 8-p-sulphophenyltheophylline 8-sulphophenyltheophylline 8-p-sulfophenyltheophylline 8-SPT 8SPT
Adenosine X X X X X
Adenosine Triphosphate   X   X X
Aorta   X    
Autonomic Nervous System X     
Cerebellum    X   
Cerebral Cortex X     
Coronary Circulation    X   
Coronary Vessels     X  
Creatine Kinase      X
Endothelium, Vascular   X    
Heart     X  
Hippocampus      X
Hyperhomocysteinemia     X  
Iris X     
Muscle Contraction X     
Muscle, Smooth    X   
Myocardial Reperfusion Injury      X
Neurons      X
Neutrophils    X   
Parasympathetic Nervous System X     
Phenethylamines   X    
Rats, Wistar     X  
Receptors, Adrenergic, alpha-1 X     
Receptors, Cell Surface    X   
Receptors, Purinergic X   X X  
Receptors, Purinergic P1   X X X  
Receptors, Purinergic P2   X    
Spinal Cord   X    
Synaptic Transmission X     
Theophylline X X X X X
Vasodilation   X   X  
Xanthines    X   
# of documents retrieved via PubMed 22 251 47 297 15