Figure 3

Volcano plot illustrating predominant sources of differentially expressed genes. Differentially expressed genes are highlighted according to a Bonferroni cutoff (red dashed line) between the high dose treatments and controls within the condition e.g. 24 hr cell (A), 48 hr cell (B) and rat (C), and between the controls of the three conditions ((24 hr cell – 48 hr cell (D), 24 hr cell -rat (E), and 48 hr cell -rat (F)).