Prediction of desmoglein-3 peptides reveals multiple shared T-cell epitopes in HLA DR4- and DR6- associated Pemphigus vulgaris

Table 1 Prediction accuracy of the DRB1*0402 peptide-binding model.

Specificity (SP) Level	Group	Sensitivity (SE)	Binding Energy Threshold (kJ/mol)
SP = 0.80	LMH	0.78	-25.55
	MH	0.81	-25.79
	H	0.65	-26.64
SP = 0.90	LMH	0.75	-25.79
	MH	0.52	-26.94
	H	0.30	-28.83
SP = 0.95	LMH	0.70	-26.94
	MH	0.42	-27.72
	H	0.25	-30.57

Sensitivity (SE) values and binding energy thresholds for DRB1*0402 peptide-binding model at specificity (SP) levels 0.80, 0.90 and 0.95.

ISSN: 1471-2105