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Table 1 Rate constants and initial populations in system (Al) used to maintain the time scale separation at ~O(104) as the population X0 increases.

From: A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellular networks

Initial Population XA = XB = XC = X0/3

Fast Network k1 = k-1 (s-1)

Slow Network k2 = k-2(s-1)

5

104

1.0

50

103

10-1

500

102

10-2

5000

10

10-3

50000

1.0

10-4

  1. The rate constants have been proportionally scaled down with increasing population to maintain the reaction propensities approximately constant.
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BMC Bioinformatics

ISSN: 1471-2105

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