Figure 1From: Requirements and ontology for a G protein-coupled receptor oligomerization knowledge baseTraditional and current views of GPCR signaling. The traditional view of GPCR signaling assumed that monomeric receptors participated in ligand binding and signal transduction. The current view suggests that GPCRs may form homo- and/or hetero-oligomers, and that ligand(s) binding to one or more receptors may activate neighboring receptors in the oligomeric complex.Back to article page