Figure 2

A flow chart of computational simulation. This flow chart outlines the basic algorithms including re-sampling, haplotype block definition, and block concordance (See Methods). x is the sample size in the re-sampling process. This parameter is increased from 50 to 700 in increments of 50, in addition to 10, 25, and 725. n is the number of repeat times of simulation under the maximum repeat time N. The θ value is an original measurement of the estimation of haplotype block, and is the ratio of times to N times when simulating the transition zone of block (See Materials and Methods). HWE denotes Hardy-Weinberg equilibrium, and MAF denotes minor allele frequencies.