Table 1 Reactions whose directions have to be reversed to restore connectivity of metabolites using mechanism 1.
From: Optimization based automated curation of metabolic reconstructions
(GapFill) identified reversible reactions in E. coli | Corresponding metabolite(s) in E. coli which is (are) fixed | Pathway |
|---|---|---|
ADOCBLS | rdmbzi, agdpcbi, adocbi, adocbip | Cofactor and Prosthetic Group Biosynthesis |
HETZK | 4mhetz | Cofactor and Prosthetic Group Biosynthesis |
HMPK1 | 4ahmmp | Cofactor and Prosthetic Group Biosynthesis |
SPODM | o2- | Unassigned |
DXYLK | dxyl | Cofactor and Prosthetic Group Biosynthesis |
ACBIPGT | adocbi, adocbip, 5prdmbz | Cofactor and Prosthetic Group Biosynthesis |
PGLYCP | 2pglyc | Alternate Carbon Metabolism |
NNDMBRT | 5prdmbz, dmbzid | Cofactor and Prosthetic Group Biosynthesis |
PEAMNO | peamn | Alternate Carbon Metabolism |
ALDD19x | peamn | Alternate Carbon Metabolism |
CRNt7 | crn, gbbtn, ctbt, crncoa*, bbtcoa, ctbtcoa | Transport, Extracellular |
AP4AH | ap4a | Nucleotide Salvage Pathways |
2DGLCNRy | 2dhglcn | Alternate Carbon Metabolism |
DKGLCNR2x | 2dhglcn, 25dkglcn | Alternate Carbon Metabolism |
BETALDHx | betald | Unassigned |
BETALDHy | betald | Unassigned |
DKGLCNR1 | 25dkglcn, 2dhglcn | Alternate Carbon Metabolism |
X5PL3E | ap5a, xu5pL, | Alternate Carbon Metabolism |
DKGLCNR2y | 25dkglcn | Alternate Carbon Metabolism |
DKGLCNR2x | 25dkglcn, 2dhglcn | Alternate Carbon Metabolism |
2DGULRx | 2dhguln | Alternate Carbon Metabolism |
2DGULRy | 2dhguln | Alternate Carbon Metabolism |
GP4GH | gp4g | Nucleotide Salvage Pathways |
DOGULNR | 23doguln, 3dhguln | Alternate Carbon Metabolism |
ADOCBIK | adocbi | Cofactor and Prosthetic Group Biosynthesis |
KG6PDC | 3dgulnp, 3dhguln | Alternate Carbon Metabolism |
RZ5PP | dmbzid | Cofactor and Prosthetic Group Biosynthesis |
GPDDA5 | g3pi | Cell Envelope Biosynthesis |
GPDDA3 | g3ps | Cell Envelope Biosynthesis |