Skip to main content

Table 3 BLAST scores of added reactions in S. cerevisiae

From: Optimization based automated curation of metabolic reconstructions

Reactions E Value Reaction in S. cerevisiae Organism
methionine γ-lyase 1e-58,1e-68 Cystathionine gamma-lyase Pseudomonas putida
2-hydroxyglutarate synthase(no gene identified yet) ---------- --------------- E. coli
2-oxoglutarate reductase/phosphoglycerate dehydrogenase 2e-14, 3e-18 3-phosphoglycerate dehydrogenase Bacillus subtilis
deoxyribose-phosphate aldolase 7.7, 0.006 Phosphatidylinositol 3-kinase TOR2 Mycoplasma pneumoniae
D-lactate dehydrogenase 2, 3e-04 Protein of unknown function E. coli
L-tryptophan aminotransferase no information no information Enterobacter cloacae
Methylglyoxal synthase 1.5, 0.001 carbamyl phosphate synthetase E. coli
phenylpyruvate decarboxylase 3E-35, 1e-39 Chain A, Pyruvate Decarboyxlase Azoarcus sp. EbN1
tagatose-1,6-bisphosphate aldolase 2 1e-12, 1e-16 Fructose 1,6-bisphosphate aldolase E. coli
tryptophan 2-monooxygenase 2.2, 5e-05 orf:PZA105 E. coli
5,10-methylenetetrahydrofolate reductase(present in the cytosol) 1E-38, 2e-42 Isozyme of methylenetetrahydrofolate reductase E. coli
adenine phosphoribosyltransferase(present in cytosol) 2E-25, 1e-29 Adenine phosphoribosyltransferase E. coli
guanylate kinase(present in cytosol) 9E-38, 7e-42 Guanylate kinase E. coli
putative NAD+ kinase(present in cytosol) 2E-27, 6e-28 ATP-NADH kinase E. coli
adenylate kinase(present in cytosol and mitochondria) 7E-51, 5e-55 Adenylate kinase E. coli
  1. Candidate reactions from the MetaCyc database (along with BLAST scores) added to enable production of no-production metabolites in S. cerevisiae.