Figure 5

cAMP-dependent protein kinase (open). Morph ID: f048180-370 PDB ID: 1ctp. Hinge Atlas Gold hinges: 31–32, 119–120, 319–320. b. Zheng et al. identify the boundaries of the small lobe as residues 40 and 127, slightly different from HAG. The single-cut predictors had significant minima near residue 120, with more ambiguous results for the other two hinges. c. 2-cut FlexOracle primary prediction: residues 314–317. Others: 30–33, 62–65. 42–45, 82–85. 122–125. The 2-cut predictor was partially successful. The primary prediction coincides with one of the hinges, as does the fourth prediction, and one of the second predictions. There are also three false positives (62–65 and 42–45, and 82–85) among the higher predictions.