Figure 9

Histogram of Shannon entropies. for amino acids participating in rare 3-grams (black) and other amino acids (dashed), based on the family memberships in the examined three cases (Src, Hb and Tyr tRNA synthetase). The abscissa shows the percentages of amino acids corresponding to bins of size Δ S = 0.25. We note the high propensity of rare residues in the range S < 0.25 corresponding to highest conservation.