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Table 4 Results obtained under Setups (1) – (3). The medians reported in the table were calculated from 100 simulations. The median est.FDR values reported in Column 4 were obtained from sam2.20 and the symmetric cutoff method directly. The median est.FDRc values reported in Column 5 are the estimated FDR with FP correction (12).

From: A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance

Setup

Median M

Median true FDR sam2.20/sym.cutoff

Median est.FDR sam2.20/sym.cut

Median est. FDRc sam2.20/sym.cut

1

 

199

0.1005/0.1005

0.1188/0.1238

0.0981/0.1020

2

(i)

210.5

0.7082/0.7779

0.6959/0.8130

0.6875/0.7945

 

(ii)

211.5

0.6699/0.6748

0.6730/0.7219

0.6331/0.6933

 

(iii)

207

0.6578/0.6533

0.6738/0.7039

0.6376/0.6616

 

(iv)

200

0.5025/0.4371

0.5305/0.4846

0.5004/0.4403

3

(i)

399

0.0599/0.0800

0.0596/0.1017

0.0598/0.0779

 

(ii)

399

0.1827/0.1754

0.1874/0.2135

0.1862/0.1758

 

(iii)

399

0.2130/0.1989

0.21750/.2462

0.2168/0.2007

 

(iv)

400.5

0.4913/0.3950

0.5067/0.4511

0.4975/0.3994