Table 5 Results obtained for the leukaemia data. Table 5 reports the number of significant positive and negative genes (columns 2, 6), the cutoffs (columns 3, 7), the estimated FDR (FDR) and the estimated FDR with FP correction (FDR-c) from sam2.20 and the symmetric cutoff method (columns 4, 8). Column 5 reports the number of genes found significant by sam2.20 and the symmetric cutoff method from the list of informative genes [21].
| sam2.20 | # of genes from Golub et al.'s list | The symmetric cutoff method | ||||
|---|---|---|---|---|---|---|---|
| Â | sig. pos | cutup | FDR | sam2.20 | sig. pos | cutup | FDR |
| Â | sig. neg | cutlo | FDR-c | sym.cut | sig. neg | cutlo | FDR-c |
316 | 227 | 3.2023 | 0.0065 | 14 | 215 | 3.3073 | 0.0043 |
| Â | 89 | -3.3888 | 0.0068 | 14 | 101 | -3.3073 | 0.0045 |
191 | 154 | 3.8648 | 0.0036 | 9 | 143 | 3.9612 | 0.0036 |
| Â | 37 | -4.2450 | 0.0037 | 11 | 48 | -3.9612 | 0.0037 |
92 | 87 | 4.0787 | 0 | 7 | 73 | 4.1906 | 0 |
| Â | 5 | -5.1595 | 0 | 9 | 19 | -4.1906 | 0 |
29 | 29 | 5.3143 | 0 | 5 | 27 | 5.3685 | 0 |
| Â | 0 | -Inf | 0 | 6 | 2 | -5.3685 | 0 |
23 | 23 | 5.5514 | 0 | 5 | 22 | 5.5678 | 0 |
| Â | 0 | -Inf | 0 | 5 | 1 | -5.5678 | 0 |