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Table 4 Overlap between clusters in physical interaction network and GO annotation

From: Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks

Biological process (public GOA)

Biological process (MedScan GOA)

Biological process (combined GOA)

Cellular component (public GOA)

Molecular function (public GOA)

54

50

54

49

54

  1. A total of 54 network clusters, each containing between 8 and 82 proteins were obtained in the given realization of Potts network clustering method [31]. The statistical significance of the overlap between every cluster and every GO group of a given annotation was evaluated using Fisher's Exact Test by computing the probability that the cluster and a GO group, drawn from the same set of ~10000 proteins at random, have the overlap not less than the observed one. The table shows the number of network clusters overlapping with at least one GO group in a given annotation with a p-value less than 0.001.
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BMC Bioinformatics

ISSN: 1471-2105

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