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Table 2 Performance comparison of modularization methods

From: Semantic integration to identify overlapping functional modules in protein interaction networks

method

number of modules

average size of modules

-log(p-value)

parameters

flow-based (semantic similarity)

178

46.14

24.42

min flow = 0.4

flow-based (semantic interactivity)

189

40.40

29.05

min flow = 0.1

CFinder

57

17.86

12.32

k = 3

betweenness-cut

57

41.02

17.44

max density = 0.03

STM

60

40.10

13.70

merging thres. = 1.0

  1. The output modules were generated by the flow-based, CFinder, betweenness-cut and STM method. The input was the core protein interaction network from DIP. The performance was evaluated by p-value.