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Table 1 Empirical type I error rates and powers of the proposed (T s ) and Zhao et al's (T z ) tests, and average percentages of perfectly estimated haplotypes for the dominant and recessive models according to 4 types of haplotype distribution (HD)

From: Haplotype-based score test for linkage in nuclear families

   Dominant Recessive
HD RR p f p o T s T z p f p o T s T z
E 1 88 72 .060 .065 88 72 .045 .050
  2 88 73 .275 .280 88 72 .145 .110
  3 88 73 .635 .645 89 73 .275 .275
  4 89 74 .815 .820 89 72 .455 .460
UE1 1 92 79 .060 .065 92 79 .050 .040
  2 92 79 .240 .235 92 79 .060 .050
  3 92 79 .560 .545 92 79 .050 .055
  4 92 79 .845 .840 93 79 .065 .055
UE2 1 99 94 .050 .065 99 94 .075 .085
  2 98 92 .270 .250 99 93 .035 .040
  3 98 90 .610 .580 99 93 .065 .055
  4 97 89 .885 .860 99 93 .065 .060
UE3 1 100 100 .040 .055 100 100 .090 .075
  2 100 100 .375 .325 100 100 .055 .065
  3 100 100 .795 .780 100 100 .060 .055
  4 100 100 .960 .950 100 100 .070 .060
  1. The rows corresponding to RR = 1 are for type I error rate, and the rows corresponding to RR = 2, 3 or 4 are for power. The columns corresponding to p f and p o are the average percentages of perfectly estimated haplotypes, respectively, when based on family trios and based on parents alone in estimating haplotype frequencies.